DCUN1D1 antibody
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- Target See all DCUN1D1 Antibodies
- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DCUN1D1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- DCN1, defective in cullin neddylation 1, domain containing 1(S. cerevisiae)
- Isotype
- IgG
- Top Product
- Discover our top product DCUN1D1 Primary Antibody
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- Application Notes
- WB: 1:500-1:2000, IHC: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
- Alternative Name
- DCUN1D1 (DCUN1D1 Products)
- Synonyms
- fd19a01 antibody, zgc:66414 antibody, wu:fd19a01 antibody, dcun1l1 antibody, rp42 antibody, sccro antibody, scro antibody, tes3 antibody, DCNL1 antibody, DCUN1L1 antibody, RP42 antibody, SCCRO antibody, SCRO antibody, Tes3 antibody, Rp42 antibody, pTes3 antibody, DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) antibody, DCN1-like protein 1 antibody, DCN1, defective in cullin neddylation 1, domain containing 1 L homeolog antibody, defective in cullin neddylation 1 domain containing 1 antibody, dcun1d1 antibody, dcnl1 antibody, dcun1d1.L antibody, DCUN1D1 antibody, Dcun1d1 antibody
- Background
- Synonyms:DCUN1L1, RP42, SCCRO Background:Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8(UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates(PubMed:25349211). Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression(By similarity).
- Molecular Weight
- 28 kDa
- Gene ID
- 54165
- UniProt
- Q96GG9
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