EPH Receptor A2 antibody

Catalog No. ABIN7113847

This Mouse Monoclonal antibody specifically detects EPH Receptor A2 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for EPH Receptor A2 antibody (ABIN7113847)

Target: EPH Receptor A2 (EPHA2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 2B8

Product Details anti-EPH Receptor A2 Antibody

Purpose: EPHA2 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Ephrin type-A receptor 2

Isotype: IgG1

Application Details

Application Notes: WB: 1:2000-1:20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Alternative Name: EPHA2

Background:

Synonyms: Ephrin type-A receptor 2|Epithelial cell kinase|Tyrosine-protein kinase receptor ECK|EPHA2|ECK

Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.

Molecular Weight: 130 kDa

UniProt: P29317

Pathways: RTK Signaling