EIF3K antibody

Catalog No. ABIN7113951

This anti-EIF3K antibody is a Rabbit Polyclonal antibody detecting EIF3K in ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for EIF3K antibody (ABIN7113951)

Target: EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3K antibody is un-conjugated

Application: ELISA

Product Details anti-EIF3K Antibody

Purpose: EIF3K antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: eukaryotic translation initiation factor 3, subunit K

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for EIF3K

Target: EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))

Alternative Name: EIF3K

Background:

Synonyms: Eukaryotic translation initiation factor 3 subunit K (eIF3k)|Eukaryotic translation initiation factor 3 subunit 12|Muscle-specific gene M9 protein|PLAC-24|eIF-3 p25|eIF-3 p28|EIF3K|EIF3S12

Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Gene ID: 27335

UniProt: Q9UBQ5

Pathways: Ribonucleoprotein Complex Subunit Organization