EYA4 antibody

Catalog No. ABIN7114031

The Rabbit Polyclonal anti-EYA4 antibody has been validated for ELISA, WB and IF. It is suitable to detect EYA4 in samples from Human and Mouse.

Quick Overview for EYA4 antibody (ABIN7114031)

Target: EYA4 (Eyes Absent Homolog 4 (EYA4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EYA4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-EYA4 Antibody

Purpose: EYA4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: eyes absent homolog 4(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for EYA4

Target: EYA4 (Eyes Absent Homolog 4 (EYA4))

Alternative Name: EYA4

Background:

Synonyms: Eyes absent homolog 4|EYA4

Background: Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX(H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye(By similarity).

Molecular Weight: 67 kDa

Gene ID: 2070

UniProt: O95677

Pathways: Sensory Perception of Sound