FBXO5 antibody (AA 1-447)

Catalog No. ABIN7114052

The Rabbit Polyclonal anti-FBXO5 antibody is suitable to detect FBXO5 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for FBXO5 antibody (AA 1-447) (ABIN7114052)

Target: FBXO5 (F-Box Protein 5 (FBXO5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-FBXO5 Antibody

Binding Specificity: AA 1-447

Purpose: FBXO5 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-447aa

Immunogen: F-box protein 5

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FBXO5

Target: FBXO5 (F-Box Protein 5 (FBXO5))

Alternative Name: FBXO5

Background:

Synonyms: F-box only protein 5|Early mitotic inhibitor 1|FBXO5|EMI1|FBX5

Background: Regulates progression through early mitosis by inhibiting the anaphase promoting complex/cyclosome(APC). Binds to the APC activators CDC20 and FZR1/CDH1 to prevent APC activation. Can also bind directly to the APC to inhibit substrate-binding.

Molecular Weight: 56 kDa, 45 kDa

Gene ID: 26271

UniProt: Q9UKT4

Pathways: Mitotic G1-G1/S Phases