FAF2 antibody (AA 251-445)

Catalog No. ABIN7114135

This Rabbit Polyclonal antibody specifically detects FAF2 in WB, ELISA, IHC, IP and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FAF2 antibody (AA 251-445) (ABIN7114135)

Target: FAF2 (Fas Associated Factor Family Member 2 (FAF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-FAF2 Antibody

Binding Specificity: AA 251-445

Purpose: FAF2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 251-445aa

Immunogen: Fas associated factor family member 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FAF2

Target: FAF2 (Fas Associated Factor Family Member 2 (FAF2))

Alternative Name: FAF2

Background:

Synonyms: FAS-associated factor 2|UBX domain-containing protein 3B|UBX domain-containing protein 8|FAF2|ETEA|KIAA0887|UBXD8|UBXN3B

Background: Plays an important role in endoplasmic reticulum-associated degradation(ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins(PubMed:18711132, PubMed:24215460). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis(PubMed:23297223).

Molecular Weight: 53 kDa

Gene ID: 23197

UniProt: Q96CS3