Hsc70 antibody

Catalog No. ABIN7114890

The Mouse Monoclonal anti-Hsc70 antibody (Clone 4E11) (ABIN7114890) specifically detects Hsc70 in WB, IHC and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Hsc70 antibody (ABIN7114890)

Target: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Hsc70 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 4E11

Product Details anti-Hsc70 Antibody

Purpose: HSPA8 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Hsc70

Isotype: IgG1

Application Details

Application Notes: WB: 1:3000-1:20000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Hsc70

Target: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Alternative Name: HSPA8

Background:

Synonyms: Heat shock cognate 71 kDa protein|Heat shock 70 kDa protein 8|Lipopolysaccharide-associated protein 1 (LAP-1, LPS-associated protein 1)|HSPA8|HSC70|HSP73|HSPA10

Background: HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson's disease, indicating its implication in neurodegenerative disease. (21832061)

Molecular Weight: 70 kDa

Gene ID: 3312

UniProt: P11142