The Rabbit Polyclonal anti-LZTS2 antibody has been validated for WB, ELISA and IHC. It is suitable to detect LZTS2 in samples from Human, Mouse and Rat.
Synonyms:KIAA1813, LAPSER1 Background:Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.