Lipase A antibody

Catalog No. ABIN7115890

This Rabbit Polyclonal antibody specifically detects Lipase A in WB, ELISA and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Lipase A antibody (ABIN7115890)

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipase A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Lipase A Antibody

Purpose: LIPA antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: lipase A, lysosomal acid, cholesterol esterase

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Lipase A

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Alternative Name: LIPA

Background:

Synonyms: Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase, LAL)|Cholesteryl esterase|Lipase A|Sterol esterase|LIPA

Background: Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL(low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.

Molecular Weight: 45 kDa

Gene ID: 3988

UniProt: P38571