LBP antibody

Catalog No. ABIN7115905

This Mouse Monoclonal antibody specifically detects LBP in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for LBP antibody (ABIN7115905)

Target: LBP (Lipopolysaccharide Binding Protein (LBP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 2B8

Product Details anti-LBP Antibody

Purpose: LBP antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: lipopolysaccharide binding protein

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for LBP

Target: LBP (Lipopolysaccharide Binding Protein (LBP))

Alternative Name: LBP

Background:

Synonyms: Lipopolysaccharide-binding protein (LBP)|LBP

Background: Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides(LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria(PubMed:7517398, PubMed:24120359). Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide(PubMed:7517398, PubMed:24120359).

Molecular Weight: 53-60 kDa

Gene ID: 3929

UniProt: P18428

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process