MAD2L1 antibody

Catalog No. ABIN7115999

The Mouse Monoclonal anti-MAD2L1 antibody is suitable to detect MAD2L1 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for MAD2L1 antibody (ABIN7115999)

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAD2L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 8G6

Product Details anti-MAD2L1 Antibody

Purpose: MAD2L1 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: MAD2 mitotic arrest deficient-like 1(yeast)

Isotype: IgG2a

Application Details

Application Notes: WB: 1:1000-1:3000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MAD2L1

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Alternative Name: MAD2L1

Background:

Synonyms: Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2)|Mitotic arrest deficient 2-like protein 1 (MAD2-like protein 1)|MAD2L1|MAD2

Background: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.

Molecular Weight: 25-30 kDa

Gene ID: 4085

UniProt: Q13257