MAPK4 antibody

Catalog No. ABIN7116423

The Rabbit Polyclonal anti-MAPK4 antibody (ABIN7116423) specifically detects MAPK4 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MAPK4 antibody (ABIN7116423)

Target: MAPK4 (Mitogen-Activated Protein Kinase 4 (MAPK4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MAPK4 Antibody

Purpose: MAPK4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: mitogen-activated protein kinase 4

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MAPK4

Target: MAPK4 (Mitogen-Activated Protein Kinase 4 (MAPK4))

Alternative Name: MAPK4

Background:

Synonyms: Mitogen-activated protein kinase 4 (MAP kinase 4, MAPK 4)|Extracellular signal-regulated kinase 4 (ERK-4)|MAP kinase isoform p63 (p63-MAPK)|MAPK4|ERK4|PRKM4

Background: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2(MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle(By similarity).

Molecular Weight: 68 kDa

Gene ID: 5596

UniProt: P31152

Pathways: MAPK Signaling