MAP2K6 antibody

Catalog No. ABIN7116449

The Rabbit Polyclonal anti-MAP2K6 antibody has been validated for WB, ELISA, IHC and FACS. It is suitable to detect MAP2K6 in samples from Human, Mouse and Rat.

Quick Overview for MAP2K6 antibody (ABIN7116449)

Target: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-MAP2K6 Antibody

Purpose: MAP2K6 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: mitogen-activated protein kinase kinase 6

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2400, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MAP2K6

Target: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Alternative Name: MAP2K6

Background:

Synonyms: Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6, MAPKK 6)|MAPK/ERK kinase 6 (MEK 6)|Stress-activated protein kinase kinase 3 (SAPK kinase 3, SAPKK-3, SAPKK3)|MAP2K6|MEK6|MKK6|PRKMK6|SKK3

Background: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein(MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases(ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

Molecular Weight: 37 kDa

Gene ID: 5608

UniProt: P52564

Pathways: MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades