ABCB1 antibody
Quick Overview for ABCB1 antibody (ABIN7117181)
Target
See all ABCB1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- ABCB1 antibody
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
- ABCB1
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Isotype
- IgG
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Application Notes
- WB: 1:200-1:1000, IP: 1:200-1:1000, IHC: 1:50-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
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Alternative Name
- ABCB1
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Background
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Synonyms: ATP-dependent translocase ABCB1|ATP-binding cassette sub-family B member 1|Multidrug resistance protein 1|P-glycoprotein 1|Phospholipid transporter ABCB1|ABCB1|MDR1|PGY1
Background: ABCB1(also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.
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Molecular Weight
- 142 kDa
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Gene ID
- 5243
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UniProt
- P08183
Target
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