TSPO antibody

Catalog No. ABIN7117327

This Rabbit Polyclonal antibody specifically detects TSPO in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TSPO antibody (ABIN7117327)

Target: TSPO (Peripheral-Type Benzodiazepine Receptor (TSPO))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPO antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-TSPO Antibody

Purpose: TSPO antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Translocator protein

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IF: 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TSPO

Target: TSPO (Peripheral-Type Benzodiazepine Receptor (TSPO))

Alternative Name: TSPO

Background:

Synonyms: Translocator protein|Mitochondrial benzodiazepine receptor|PKBS|Peripheral-type benzodiazepine receptor (PBR)|TSPO|BZRP|MBR

Background: Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported, one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.

Molecular Weight: 19 kDa

UniProt: P30536

Pathways: Cellular Response to Molecule of Bacterial Origin