PHF21A antibody

Catalog No. ABIN7117378

This Rabbit Polyclonal antibody specifically detects PHF21A in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PHF21A antibody (ABIN7117378)

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF21A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PHF21A Antibody

Purpose: PHF21A antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: PHD finger protein 21A

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PHF21A

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Alternative Name: PHF21A

Background:

Synonyms: PHD finger protein 21A|BHC80a|BRAF35-HDAC complex protein BHC80|PHF21A|BHC80|KIAA1696

Background: Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation.

Molecular Weight: 75 kDa

Gene ID: 51317

UniProt: Q96BD5

Pathways: Feeding Behaviour