PDE5A antibody (AA 1-150)

Catalog No. ABIN7117430

The Rabbit Polyclonal anti-PDE5A antibody is suitable to detect PDE5A in samples from Human, Rat and Mouse. It has been validated for WB, ELISA and IF.

Quick Overview for PDE5A antibody (AA 1-150) (ABIN7117430)

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE5A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-PDE5A Antibody

Binding Specificity: AA 1-150

Purpose: PDE5A antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-150aa

Immunogen: phosphodiesterase 5A, cGMP-specific

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PDE5A

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Alternative Name: PDE5A

Background:

Synonyms: cGMP-specific 3',5'-cyclic phosphodiesterase|cGMP-binding cGMP-specific phosphodiesterase (CGB-PDE)|PDE5A|PDE5

Background: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP(PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide-generated cGMP(PubMed:15489334).

Molecular Weight: 100 kDa

Gene ID: 8654

UniProt: O76074

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling