PITRM1 antibody

Catalog No. ABIN7117536

This anti-PITRM1 antibody is a Rabbit Polyclonal antibody detecting PITRM1 in WB, IHC and ELISA. Suitable for Human, Rat and Mouse.

Quick Overview for PITRM1 antibody (ABIN7117536)

Target: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PITRM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PITRM1 Antibody

Purpose: PITRM1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: pitrilysin metallopeptidase 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PITRM1

Target: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Alternative Name: PITRM1

Background:

Synonyms: Presequence protease, mitochondrial (hPreP)|Pitrilysin metalloproteinase 1 (Metalloprotease 1, hMP1)|PITRM1|KIAA1104|MP1|PREP

Background: The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.

Molecular Weight: 117 kDa

Gene ID: 10531

UniProt: Q5JRX3

Pathways: PI3K-Akt Signaling, SARS-CoV-2 Protein Interactome