PHIP antibody

Catalog No. ABIN7117590

This anti-PHIP antibody is a Rabbit Polyclonal antibody detecting PHIP in WB, ELISA and IHC. Suitable for Human and Mouse.

Quick Overview for PHIP antibody (ABIN7117590)

Target: PHIP (Pleckstrin Homology Domain Interacting Protein (PHIP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHIP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PHIP Antibody

Purpose: PHIP antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: pleckstrin homology domain interacting protein

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PHIP

Target: PHIP (Pleckstrin Homology Domain Interacting Protein (PHIP))

Alternative Name: PHIP

Background:

Synonyms: PH-interacting protein (PHIP)|DDB1- and CUL4-associated factor 14|IRS-1 PH domain-binding protein|WD repeat-containing protein 11|PHIP|DCAF14|WDR11

Background: This gene encodes a protein that binds to the insulin receptor substrate 1 protein and regulates glucose transporter translocation in skeletal muscle cells. The encoded protein may also regulate growth and survival of pancreatic beta cells. Elevated copy number of this gene may be associated with melanoma severity and the encoded protein may promote melanoma metastasis in human patients.

Molecular Weight: 250 kDa

Gene ID: 55023

UniProt: Q8WWQ0

Pathways: Protein targeting to Nucleus