KCNJ5 antibody

Catalog No. ABIN7117715

The Rabbit Polyclonal anti-KCNJ5 antibody has been validated for WB and ELISA. It is suitable to detect KCNJ5 in samples from Human, Rat and Mouse.

Quick Overview for KCNJ5 antibody (ABIN7117715)

Target: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KCNJ5 Antibody

Purpose: KCNJ5 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: potassium inwardly-rectifying channel, subfamily J, member 5

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for KCNJ5

Target: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Alternative Name: KCNJ5

Background:

Synonyms: G protein-activated inward rectifier potassium channel 4 (GIRK-4)|Cardiac inward rectifier (CIR)|Heart KATP channel|Inward rectifier K(+) channel Kir3.4 (IRK-4)|KATP-1|Potassium channel, inwardly rectifying subfamily J member 5|KCNJ5|GIRK4

Background: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.

Molecular Weight: 47 kDa

Gene ID: 3762

UniProt: P48544

Pathways: Notch Signaling