PDCD6 antibody

Catalog No. ABIN7117800

This anti-PDCD6 antibody is a Rabbit Polyclonal antibody detecting PDCD6 in WB, ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for PDCD6 antibody (ABIN7117800)

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PDCD6 Antibody

Purpose: PDCD6 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: programmed cell death 6

Isotype: IgG

Application Details

Application Notes: WB: 1:200 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PDCD6

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Alternative Name: PDCD6

Background:

Synonyms: Programmed cell death protein 6|Apoptosis-linked gene 2 protein homolog (ALG-2)|PDCD6|ALG2

Background: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

Molecular Weight: 16 kDa

Gene ID: 10016

UniProt: O75340

Pathways: Positive Regulation of Endopeptidase Activity