PTGDS antibody
Quick Overview for PTGDS antibody (ABIN7117860)
Target
See all PTGDS AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
- prostaglandin D2 synthase 21kDa (brain)
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Isotype
- IgG
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Application Notes
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Expiry Date
- 12 months
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- PTGDS (Prostaglandin D2 Synthase (PTGDS))
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Alternative Name
- PTGDS
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Background
- Synonyms:PDS Background:The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
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Molecular Weight
- 33 kDa
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Gene ID
- 5730
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UniProt
- P41222
Target
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