RNASEH2C antibody

Catalog No. ABIN7118518

This Rabbit Polyclonal antibody specifically detects RNASEH2C in WB, ELISA, IHC and IP. It exhibits reactivity toward Human.

Quick Overview for RNASEH2C antibody (ABIN7118518)

Target: RNASEH2C (Ribonuclease H2, Subunit C (RNASEH2C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASEH2C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-RNASEH2C Antibody

Purpose: RNASEH2C antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ribonuclease H2, subunit C

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:1000, IHC: 1:20-1:200, IP: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RNASEH2C

Target: RNASEH2C (Ribonuclease H2, Subunit C (RNASEH2C))

Alternative Name: RNASEH2C

Background:

Synonyms: Ribonuclease H2 subunit C (RNase H2 subunit C)|Aicardi-Goutieres syndrome 3 protein (AGS3)|RNase H1 small subunit|Ribonuclease HI subunit C|RNASEH2C|AYP1

Background: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.

Molecular Weight: 20 kDa

Gene ID: 84153

UniProt: Q8TDP1