RNF135 antibody

Catalog No. ABIN7118637

The Rabbit Polyclonal anti-RNF135 antibody (ABIN7118637) specifically detects RNF135 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for RNF135 antibody (ABIN7118637)

Target: RNF135 (Ring Finger Protein 135 (RNF135))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF135 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RNF135 Antibody

Purpose: RNF135 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ring finger protein 135

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RNF135

Target: RNF135 (Ring Finger Protein 135 (RNF135))

Alternative Name: RNF135

Background:

Synonyms: E3 ubiquitin-protein ligase RNF135|RIG-I E3 ubiquitin ligase (REUL)|RING finger protein 135|RING finger protein leading to RIG-I activation (Riplet)|RING-type E3 ubiquitin transferase RNF135|RNF135

Background: Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production.

Molecular Weight: 48 kDa

Gene ID: 84282

UniProt: Q8IUD6