RBPMS antibody

Catalog No. ABIN7118698

This Rabbit Polyclonal antibody specifically detects RBPMS in WB, ELISA, IHC, FACS and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for RBPMS antibody (ABIN7118698)

Target: RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBPMS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-RBPMS Antibody

Purpose: RBPMS antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: RNA binding protein with multiple splicing

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RBPMS

Target: RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))

Alternative Name: RBPMS

Background:

Synonyms: RNA-binding protein with multiple splicing (RBP-MS)|Heart and RRM expressed sequence (Hermes)|RBPMS|HERMES

Background: Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins(PubMed:26347403). Binds to poly(A) RNA(PubMed:17099224, PubMed:26347403).

Molecular Weight: 28-30 kDa

Gene ID: 11030

UniProt: Q93062