SF3A3 antibody

Catalog No. ABIN7119434

The Rabbit Polyclonal anti-SF3A3 antibody is suitable to detect SF3A3 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, IF, ELISA and IP.

Quick Overview for SF3A3 antibody (ABIN7119434)

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

Product Details anti-SF3A3 Antibody

Purpose: SF3A3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: splicing factor 3a, subunit 3, 60kDa

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SF3A3

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Alternative Name: SF3A3

Background:

Synonyms: Splicing factor 3A subunit 3|SF3a60|Spliceosome-associated protein 61 (SAP 61)|SF3A3|SAP61

Background: Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence(BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.

Molecular Weight: 59 kDa

Gene ID: 10946

UniProt: Q12874

Pathways: Ribonucleoprotein Complex Subunit Organization