UBA2
Reactivity: Human, Rat, Dog, Monkey
WB, IHC, IF
Host: Mouse
Monoclonal
4A3
unconjugated
Application Notes
WB: 1:500-1:5000, IP: 1:200-1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target
UBA2
(SUMO1 Activating Enzyme Subunit 2 (UBA2))
Alternative Name
UBA2
Background
Synonyms:ARX, FLJ13058, HRIHFB2115, SAE2, UBA2, UBLE1B Background:The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.