UBA2 antibody (C-Term)

Catalog No. ABIN7180278

Product Details anti-UBA2 Antibody

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human Uba2.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UBA2

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Alternative Name: UBA2 (UBA2 Products)

Synonyms: ATSAE2 antibody, EMB2764 antibody, EMBRYO DEFECTIVE 2764 antibody, F3K23.23 antibody, F3K23_23 antibody, SUMO-ACTIVATING ENZYME 2 antibody, SUMO-activating enzyme 2 antibody, ARX antibody, SAE2 antibody, AA986091 antibody, Arx antibody, Sae2 antibody, UBA1 antibody, Ubl1a2 antibody, Uble1b antibody, sae2 antibody, sae2-B antibody, uba2-a antibody, uba2-b antibody, uble1b-B antibody, sae2b antibody, uble1b antibody, wu:fi17g06 antibody, zgc:66354 antibody, SUMO1 activating enzyme subunit 2 antibody, SUMO-activating enzyme 2 antibody, ubiquitin like modifier activating enzyme 2 antibody, ubiquitin-like modifier activating enzyme 2 antibody, ubiquitin like modifier activating enzyme 2 L homeolog antibody, MICPUN_63834 antibody, MICPUCDRAFT_36729 antibody, SAE2 antibody, UBA2 antibody, Uba2 antibody, uba2.L antibody, uba2 antibody

Background:

Background: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Mark H. L. Lambermon, Mol. Cell. Biol., Jun 2002, 22: 4346 - 4357.
Kyoung-Seok Ryu, J. Biol. Chem., Sep 2003, 278: 36621 - 36627.
R. Jrgen Dohmen, J. Biol. Chem., Jul 1995, 270: 18099.
Yoshiaki Azuma, FASEB J, Jun 2001, 10.1096.

Aliases: Anthracycline associated resistance ARX antibody, Anthracycline-associated resistance ARX antibody, ARX antibody, FLJ13058 antibody, HRIHFB2115 antibody, SAE 2 antibody, SAE2 antibody, SAE2_HUMAN antibody, SUMO 1 activating enzyme subunit 2 antibody, SUMO activating enzyme subunit 2 antibody, SUMO-activating enzyme subunit 2 antibody, UBA2 antibody, UBA2 ubiquitin activating enzyme E1 homolog antibody, Ubiquitin like 1 activating enzyme E1B antibody, Ubiquitin like modifier activating enzyme 2 antibody, Ubiquitin-like 1-activating enzyme E1B antibody, UBLE1B antibody

UniProt: Q9UBT2