TCF7L1 antibody

Catalog No. ABIN7120059

This anti-TCF7L1 antibody is a Rabbit Polyclonal antibody detecting TCF7L1 in WB, ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for TCF7L1 antibody (ABIN7120059)

Target: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF7L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TCF7L1 Antibody

Purpose: TCF7L1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: transcription factor 7-like 1(T-cell specific, HMG-box)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TCF7L1

Target: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Alternative Name: TCF7L1

Background:

Synonyms: Transcription factor 7-like 1|HMG box transcription factor 3 (TCF-3)|TCF7L1|TCF3

Background: Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis(By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.

Molecular Weight: 63 kDa

Gene ID: 83439

UniProt: Q9HCS4

Pathways: WNT Signaling, Stem Cell Maintenance