UCHL1 antibody

Catalog No. ABIN7120475

The Mouse Monoclonal anti-UCHL1 antibody has been validated for WB, IHC, ELISA and IF. It is suitable to detect UCHL1 in samples from Human, Rat, Mouse and Pig.

Quick Overview for UCHL1 antibody (ABIN7120475)

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Reactivity: Human, Rat, Mouse, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This UCHL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 1H7

Product Details anti-UCHL1 Antibody

Purpose: UCHL1 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ubiquitin carboxyl-terminal esterase L1(ubiquitin thiolesterase)

Isotype: IgG1

Application Details

Application Notes: WB: 1:5000-1:50000, IF: 1:20-1:200, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for UCHL1

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Alternative Name: UCHL1

Background:

Synonyms: Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)|Neuron cytoplasmic protein 9.5|PGP 9.5 (PGP9.5)|Ubiquitin thioesterase L1|UCHL1

Background: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.

Molecular Weight: 26 kDa

Gene ID: 7345

UniProt: P09936

Pathways: Feeding Behaviour