VTA1 antibody

Catalog No. ABIN7120797

Product Details anti-VTA1 Antibody

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VTA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Vps20-associated 1 homolog(S. cerevisiae)

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000,IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for VTA1

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Alternative Name: VTA1 (VTA1 Products)

Synonyms: C6orf55 antibody, DRG-1 antibody, DRG1 antibody, LIP5 antibody, My012 antibody, SBP1 antibody, 1110001D18Rik antibody, 1110059P08Rik antibody, AU040813 antibody, C85340 antibody, Lip5 antibody, RGD1305031 antibody, Vps20-associated 1 homolog antibody, vesicle trafficking 1 antibody, vesicle (multivesicular body) trafficking 1 antibody, Vta1 antibody, VTA1 antibody

Background: Synonyms:C6orf55, DRG 1, DRG1, FLJ27228, HSPC228, LIP5, LYST interacting protein 5, My012, SBP1, SKD1 binding protein 1, VTA1 Background:Involved in the endosomal multivesicular bodies(MVB) pathway. MVBs contain intraluminal vesicles(ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR(By similarity). Involved in HIV-1 budding.

Molecular Weight: 45 kDa

Gene ID: 51534

UniProt: Q9NP79