WDR77 antibody

Catalog No. ABIN7120830

The Rabbit Polyclonal anti-WDR77 antibody (ABIN7120830) specifically detects WDR77 in ELISA, WB, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for WDR77 antibody (ABIN7120830)

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR77 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-WDR77 Antibody

Purpose: WDR77 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: WD repeat domain 77

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for WDR77

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Alternative Name: WDR77

Background:

Synonyms: Methylosome protein WDR77|Androgen receptor cofactor p44|Methylosome protein 50 (MEP-50)|WD repeat-containing protein 77|p44/Mep50|WDR77|MEP50|WD45

Background: The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 40 kDa

Gene ID: 79084

UniProt: Q9BQA1

Pathways: Ribonucleoprotein Complex Subunit Organization