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JunB antibody

The Mouse Monoclonal anti-JunB antibody has been validated for IF and FACS. It is suitable to detect JunB in samples from Human.
Catalog No. ABIN7126608

Quick Overview for JunB antibody (ABIN7126608)

Target

See all JunB (JUNB) Antibodies
JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Reactivity

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Human

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This JunB antibody is un-conjugated

Application

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Immunofluorescence (IF), Flow Cytometry (FACS)
  • Specificity

    The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.

    Cross-Reactivity (Details)

    Human

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Recombinant full-length human JUNB protein

    Isotype

    IgG1
  • Application Notes

    Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, K562 or MCF-7 cells.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Preservative

    Azide free

    Storage

    -20 °C,-80 °C

    Storage Comment

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Expiry Date

    24 months
  • Target

    JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

    Alternative Name

    JUNB

    Background

    Activator protein 1 (AP1), Transcription factor junB, junB proto oncogene 9,JUNB
    Cellular localisation: Nucleus

    Molecular Weight

    39kDa

    Gene ID

    3726, 25292

    UniProt

    P17275
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