Phosphoglucomutase 5 antibody

Catalog No. ABIN7126784

Product Details anti-Phosphoglucomutase 5 Antibody

Target: Phosphoglucomutase 5 (PGM5)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Phosphoglucomutase 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Coating (Coat), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity: Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome.

Cross-Reactivity (Details): Human, Cow, Mouse, Rat and Rabbit. Predicted to react with Porcine, Avian, and Frog.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Cytoskeletal fraction of the human myometrium tissue extract

Isotype: IgG2a

Application Details

Application Notes:

Known_Application: ELISA (For coating, order antibody without BSA), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Human heart muscle or smooth muscle (IHC). Mouse heart tissue lysate (WB).

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for Phosphoglucomutase 5

Target: Phosphoglucomutase 5 (PGM5)

Alternative Name: PGM5 (PGM5 Products)

Synonyms: PGM5 antibody, si:dkey-91m11.4 antibody, PGMRP antibody, 4833423B07 antibody, 9530034F03Rik antibody, D830025G17 antibody, aciculin antibody, phosphoglucomutase 5 antibody, PGM5 antibody, pgm5 antibody, Pgm5 antibody

Background: Aciculin, PGM-RP, PGM5, PGMRP, phosphoglucomutase 5, Phosphoglucomutase-like protein 5, Phosphoglucomutase-related protein,Aciculin / Phosphoglucomutase 5 (PGM5)
Cellular localisation: Cytoplasm

Molecular Weight: 56kDa

Gene ID: 5239, 307835

UniProt: Q15124

Pathways: Cellular Glucan Metabolic Process