Recombinant Phosphoglucomutase 5 antibody
Quick Overview for Recombinant Phosphoglucomutase 5 antibody (ABIN7863234)
Target
See all Phosphoglucomutase 5 (PGM5) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Recombinant Aciculin / Phosphoglucomutase 5 (PGM5) Antibody
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Specificity
- Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Cytoskeletal fraction of the human myometrium tissue extract
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Isotype
- IgG, kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Expiry Date
- 24 months
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- Phosphoglucomutase 5 (PGM5)
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Alternative Name
- Aciculin
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Background
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Aciculin, PGM-RP, PGM5, PGMRP, phosphoglucomutase 5, Phosphoglucomutase-like protein 5, Phosphoglucomutase-related protein
Human heart muscle or skeletal muscle (IHC). skeletal muscle, PC3, heart tissue lysate (WB).
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Molecular Weight
- 56kDa
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Gene ID
- 5239, 307835
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UniProt
- Q15124
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Pathways
- Cellular Glucan Metabolic Process
Target
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