Resistin antibody (AA 19-108)

Catalog No. ABIN7126844

This Mouse Monoclonal antibody specifically detects Resistin in IHC. It exhibits reactivity toward Human.

Quick Overview for Resistin antibody (AA 19-108) (ABIN7126844)

Target: Resistin (RETN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Resistin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: RETN-3331

Product Details anti-Resistin Antibody

Binding Specificity: AA 19-108

Purpose: Resistin (RETN) Antibody

Specificity: The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to Insulin) also known as ADSF, is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like °™ is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, resistinlike æ, is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like æ expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.

Cross-Reactivity (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human RETN protein (around aa 19-108) (exact sequence is proprietary)

Isotype: IgG2b, kappa

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human bone marrow or spleen.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Resistin

Target: Resistin (RETN)

Alternative Name: RETN

Background:

Adipose tissue specific secretory factor, ADSF, C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, dri, FIZZ3, Found in inflammatory zone 3, HXCP1, Resistin delta2, RETN1, RSTN, XCP1

Human bone marrow or spleen.

Molecular Weight: ~13kDa

Gene ID: 56729, 283091

UniProt: Q9HD89

Pathways: Feeding Behaviour, Smooth Muscle Cell Migration