CCL8 antibody (AA 24-98)

Catalog No. ABIN7126921

The Mouse Monoclonal anti-CCL8 antibody is suitable to detect CCL8 in samples from Human. It has been validated for IHC.

Quick Overview for CCL8 antibody (AA 24-98) (ABIN7126921)

Target: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCL8 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: CCL8-3312

Product Details anti-CCL8 Antibody

Binding Specificity: AA 24-98

Purpose: Monocyte Chemotactic Protein 2 (MCP2) / CCL8 Antibody

Specificity: This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.

Cross-Reactivity (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Human recombinant MCP2 / CCL8 protein fragment (around aa24-98) (exact sequence is proprietary)

Isotype: IgG2b, kappa

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human small intestine, spleen or adrenal gland tissue.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CCL8

Target: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Alternative Name: CCL8

Background:

HC14, MCP2, MCP-2, SCYA8, SCYA10

Human small intestine, spleen or adrenal gland tissue.

Molecular Weight: 11kDa

Gene ID: 6355, 271387

UniProt: P80075