ZNF276 antibody

Catalog No. ABIN7127159

Product Details anti-ZNF276 Antibody

Target: ZNF276 (Zinc Finger Protein 276 (ZNF276))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZNF276 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Coating (Coat), Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers, the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene, which encodes a DNA repair protein, is situated at the same chromosomal location as the ZNF276 gene, suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia, an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human ZNF276 protein

Isotype: IgG2b

Application Details

Application Notes:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or K562 cells.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for ZNF276

Target: ZNF276 (Zinc Finger Protein 276 (ZNF276))

Alternative Name: ZNF276 (ZNF276 Products)

Synonyms: ZFP276 antibody, ZNF276 antibody, AW048709 antibody, D8Ertd370e antibody, D8Ertd377e antibody, Znf276 antibody, CENP-Z antibody, CENPZ antibody, ZNF477 antibody, zinc finger protein 276 antibody, zinc finger protein (C2H2 type) 276 antibody, ZNF276 antibody, Zfp276 antibody

Background: AW048709, D8Ertd370e, D8Ertd377e, FLJ38685, FLJ77809, HGNC:23330, ZFP276, Zinc finger protein (C2H2 type) 276, Zinc finger protein 276, Zinc finger protein 276 homolog, Zinc finger protein 477, ZNF276, ZNF477,ZNF276 (Transcription Factor)
Cellular localisation: Nucleus. Nucleoplasm.

Molecular Weight: 67kDa

Gene ID: 92822, 290154

UniProt: Q8N554