ZNF276 antibody

Catalog No. ABIN7863602

This Mouse Monoclonal antibody specifically detects ZNF276 in ELISA, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for ZNF276 antibody (ABIN7863602)

Target: ZNF276 (Zinc Finger Protein 276 (ZNF276))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZNF276 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-ZNF276-1A5

Product Details anti-ZNF276 Antibody

Purpose: ZNF276 (Transcription Factor) Antibody

Specificity: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers, the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene, which encodes a DNA repair protein, is situated at the same chromosomal location as the ZNF276 gene, suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia, an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human ZNF276 protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for ZNF276

Target: ZNF276 (Zinc Finger Protein 276 (ZNF276))

Alternative Name: ZNF276

Background:

AW048709, D8Ertd370e, D8Ertd377e, FLJ38685, FLJ77809, HGNC:23330, ZFP276, Zinc finger protein (C2H2 type) 276, Zinc finger protein 276, Zinc finger protein 276 homolog, Zinc finger protein 477, ZNF276, ZNF477

HeLa or K562 cells.

Molecular Weight: ~67kDa

Gene ID: 92822, 290154

UniProt: Q8N554