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Recombinant TXN antibody

The Rabbit Monoclonal anti-TXN antibody has been validated for WB and ELISA. It is suitable to detect TXN in samples from Human.
Catalog No. ABIN7127856

Quick Overview for Recombinant TXN antibody (ABIN7127856)

Target

See all TXN Antibodies
TXN (Thioredoxin (TXN))

Antibody Type

Recombinant Antibody

Reactivity

  • 105
  • 39
  • 30
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 103
  • 48
Rabbit

Clonality

  • 85
  • 66
Monoclonal

Conjugate

  • 90
  • 19
  • 15
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
This TXN antibody is un-conjugated

Application

  • 114
  • 78
  • 63
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  • 35
  • 18
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  • 4
  • 4
  • 3
  • 2
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  • 1
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  • 1
Western Blotting (WB), ELISA

Clone

3G7
  • Cross-Reactivity

    Human, Rat

    Purification

    Affinity-chromatography

    Immunogen

    A synthesized peptide derived from human TRX1

    Isotype

    IgG
  • Application Notes

    Recommended dilution: WB:1:500-1:5000,

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    TXN (Thioredoxin (TXN))

    Alternative Name

    TXN

    Background

    Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.

    Aliases: Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP), TXN, TRDX TRX TRX1

    UniProt

    P10599

    Pathways

    Carbohydrate Homeostasis, Cell RedoxHomeostasis
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