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ACOT8 antibody (AA 31-130)

ACOT8 Reactivity: Human ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN708641
  • Target See all ACOT8 Antibodies
    ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))
    Binding Specificity
    • 15
    • 14
    • 9
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-130
    Reactivity
    • 48
    • 14
    • 5
    • 3
    Human
    Host
    • 46
    • 3
    Rabbit
    Clonality
    • 48
    • 1
    Polyclonal
    Conjugate
    • 22
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACOT8 antibody is un-conjugated
    Application
    • 30
    • 23
    • 18
    • 14
    • 12
    • 12
    • 9
    • 7
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ACOT8
    Isotype
    IgG
    Top Product
    Discover our top product ACOT8 Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))
    Alternative Name
    ACOT8 (ACOT8 Products)
    Synonyms
    PTE1 antibody, zgc:101691 antibody, HNAACTE antibody, PTE-1 antibody, PTE-2 antibody, PTE2 antibody, hACTE-III antibody, hTE antibody, Pte1 antibody, acyl-CoA thioesterase 8 antibody, ACOT8 antibody, acot8 antibody, Acot8 antibody
    Background

    Synonyms: ACTEIII, Acot8, ACOT8_HUMAN, acyl CoA thioesterase 8, Acyl-CoA thioesterase 8, Acyl-coenzyme A thioesterase 8, Choloyl coenzyme A thioesterase, Choloyl-coenzyme A thioesterase, hACTE III, hACTE-III, hACTEIII, HIV Nef associated acyl CoA thioesterase, HIV-Nef-associated acyl-CoA thioesterase, HNAACTE, hTE, Long chain fatty acyl CoA hydrolase, Palmitoyl CoA hydrolase, Peroxisomal acyl CoA thioesterase 1, Peroxisomal acyl coenzyme A thioester hydrolase 1, Peroxisomal acyl-coenzyme A thioester hydrolase 1, Peroxisomal long chain acyl CoA thioesterase 1, Peroxisomal long-chain acyl-CoA thioesterase 1, PTE 1, PTE 2, PTE-1, PTE-2, PTE1, PTE2, Thioesterase II.

    Background: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Acyl-coenzyme A Thioesterase 8, also known as ACOT8 may mediate Nef-induced down-regulation of CD4. It is a major thioesterase in peroxisomes and competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). It shows a preference for medium-length fatty acyl-CoAs and may be involved in the metabolic regulation of peroxisome proliferation.

    Gene ID
    10005
    Pathways
    Monocarboxylic Acid Catabolic Process
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