PRCP antibody

Catalog No. ABIN7130695

This anti-PRCP antibody is a Rabbit Polyclonal antibody detecting PRCP in WB, IHC and ELISA. Suitable for Human.

Quick Overview for PRCP antibody (ABIN7130695)

Target: PRCP (Prolylcarboxypeptidase (PRCP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRCP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PRCP Antibody

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human PRCP

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PRCP

Target: PRCP (Prolylcarboxypeptidase (PRCP))

Alternative Name: PRCP

Background:

Background: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH , but the enzyme activity is retained with some substrates at neutral pH . This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Aliases: Angiotensinase C antibody, HUMPCP antibody, Lysosomal carboxypeptidase C antibody, Lysosomal Pro X carboxypeptidase antibody, Lysosomal Pro-X carboxypeptidase antibody, MGC2202 antibody, PCP antibody, PCP_HUMAN antibody, PRCP antibody, Proline carboxypeptidase antibody, Prolylcarboxypeptidase (angiotensinase C) antibody, Prolylcarboxypeptidase antibody, prolylcarboxypeptidase isoform 1 preproprotein antibody

UniProt: P42785