Paxillin antibody (pSer272)
Quick Overview for Paxillin antibody (pSer272) (ABIN7138525)
Target
See all Paxillin (PXN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer272
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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Immunogen
- Peptide sequence around phosphorylation site of Serine 272(M-A-S(p)-L-S) derived from Human Paxillin.
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Isotype
- IgG
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Application Notes
- WB:1:500-1:1000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Paxillin (PXN)
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Alternative Name
- PXN
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Background
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Background:
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
S Chen L.B., Griffin J.D. J. Biol. Chem. 270:5039-5047(1995)
Bell G.I.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databasesAliases: FLJ16691 antibody, FLJ23042 antibody, Paired box protein Pax 1 antibody, PAX 1 antibody, PAX1 antibody, PAXI_HUMAN antibody, Paxillin alpha antibody, Paxillin antibody, PXN antibody, PXN protein antibody
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UniProt
- P49023
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Pathways
- MAPK Signaling, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Target
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