CDC25B antibody (pSer323)

Catalog No. ABIN7138555

The Rabbit Polyclonal anti-CDC25B antibody (ABIN7138555) specifically detects CDC25B in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for CDC25B antibody (pSer323) (ABIN7138555)

Target: CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC25B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CDC25B Antibody

Binding Specificity: pSer323

Purpose: Phospho-CDC25B (Ser323) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 323 (S-P-S(p)-M-P) derived from Human CDC25B.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CDC25B

Target: CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

Alternative Name: CDC25B

Background:

Background: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.

Aliases: AI604853 antibody, Cdc 25B antibody, Cdc25b antibody, CDC25HU2 antibody, Cdc25m2 antibody, Cell division cycle 25 homolog B antibody, Cell division cycle 25B antibody, Cell division cycle 25B isoform 1 antibody, Cell division cycle 25B isoform 2 antibody, Cell division cycle 25B isoform 3 antibody, Cell division cycle 25B isoform 4 antibody, Cell division cycle 25B isoform 5 antibody, Dual specificity phosphatase Cdc25B antibody, EC 3.1.3.48 antibody, M phase inducer phosphatase 2 antibody, M-phase inducer phosphatase 2 antibody, MPIP2_HUMAN antibody

UniProt: P30305

Pathways: Cell Division Cycle, M Phase, Autophagy