MUC1 antibody (pTyr1229)

Catalog No. ABIN7138924

This anti-MUC1 antibody is a Rabbit Polyclonal antibody detecting MUC1 in IHC, WB, ELISA and IF. Suitable for Human.

Quick Overview for MUC1 antibody (pTyr1229) (ABIN7138924)

Target: MUC1 (Mucin 1 (MUC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-MUC1 Antibody

Binding Specificity: pTyr1229

Cross-Reactivity: Human

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 1229 S-P-Y(p)-E-K) derived from Human CD227/MUC1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MUC1

Target: MUC1 (Mucin 1 (MUC1))

Alternative Name: MUC1

Background:

Background:

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.

Lan M.S., J. Biol. Chem. 265:15294-15299(1990).
Ligtenberg M.J.L., J. Biol. Chem. 265:5573-5578(1990).
Gendler S.J., J. Biol. Chem. 265:15286-15293(1990)

Aliases: ADMCKD antibody, ADMCKD1 antibody, Breast carcinoma associated antigen DF3 antibody, Breast carcinoma-associated antigen DF3 antibody, CA 15-3 antibody, CA15 3 antibody, CA15 3 antigen antibody, CA15-3 antibody, CA15.3 antibody, Cancer antigen 15-3 antibody, Carcinoma associated mucin antibody, Carcinoma-associated mucin antibody, CD 227 antibody, CD227 antibody, DF3 antigen antibody, EMA antibody, Episialin antibody, Epithelial Membrane Antigen antibody, H23 antigen antibody, H23AG antibody, KL 6 antibody, KL-6 antibody, KL6 antibody, Krebs von den Lungen-6 antibody, MAM 6 antibody, MAM6 antibody, MCD antibody, MCKD antibody, MCKD1 antibody, Medullary cystic kidney disease 1 (autosomal dominant) antibody, Medullary cystic kidney disease, autosomal dominant antibody, MUC 1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1 antibody, MUC1-alpha antibody, MUC1-beta antibody, MUC1-CT antibody, MUC1-NT antibody, MUC1/ZD antibody, MUC1_HUMAN antibody, Mucin 1 antibody, Mucin 1 cell surface associated antibody, Mucin 1 transmembrane antibody, Mucin 1, cell surface associated antibody, Mucin-1 subunit beta antibody, Peanut reactive urinary mucin antibody, Peanut-reactive urinary mucin antibody, PEM antibody, PEMT antibody, Polymorphic epithelial mucin antibody, PUM antibody, Tumor associated epithelial membrane antigen antibody, Tumor associated epithelial mucin antibody, Tumor associated mucin antibody, Tumor-associated epithelial membrane antigen antibody, Tumor-associated mucin antibody

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling