GRIN2B antibody (pTyr1336)

Catalog No. ABIN7139096

This Rabbit Polyclonal antibody specifically detects GRIN2B in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for GRIN2B antibody (pTyr1336) (ABIN7139096)

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIN2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GRIN2B Antibody

Binding Specificity: pTyr1336

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Tyrosine1336 (S-P-Y(p)-A-H) derived from Human NMDAR2B.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GRIN2B

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Alternative Name: GRIN2B

Background:

Background:

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.

Morel V, et al. (2013) Eur J Pharmacol 721, 382-90. Peng HY, et al. (2010)Am J Physiol Renal Physiol 298, F109-17. Wu HY, et al. (2007) J Biol Chem 282, 20075-87.

Aliases: AW490526 antibody, EIEE27 antibody, Glutamate [NMDA] receptor subunit epsilon 2 antibody, Glutamate [NMDA] receptor subunit epsilon-2 antibody, Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody, Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody, Glutamate receptor ionotropic NMDA2B antibody, Glutamate receptor subunit epsilon 2 antibody, Glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody, GRIN 2B antibody, GRIN2B antibody, hNR 3 antibody, hNR3 antibody, MGC142178 antibody, MGC142180 antibody, MRD6 antibody, N methyl D asparate receptor channel subunit epsilon 2 antibody, N methyl D aspartate receptor subtype 2B antibody, N methyl D aspartate receptor subunit 2B antibody, N methyl D aspartate receptor subunit 3 antibody, N-methyl D-aspartate receptor subtype 2B antibody, N-methyl-D-aspartate receptor subunit 3 antibody, NMDA NR2B antibody, NMDA R2B antibody, NMDAR2B antibody, NMDE2 antibody, NMDE2_HUMAN antibody, NME2 antibody, NR2B antibody, NR3 antibody

UniProt: Q13224

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity