H2AFZ antibody (H2A.ZK7ac)

Catalog No. ABIN7139193

The Rabbit Polyclonal anti-H2AFZ antibody is suitable to detect H2AFZ in samples from Human. It has been validated for WB, ELISA, ICC, IF, ChIP and IP.

Quick Overview for H2AFZ antibody (H2A.ZK7ac) (ABIN7139193)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFZ antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP)

Product Details anti-H2AFZ Antibody

Binding Specificity: H2A.ZK7ac

Purpose: Acetyl-H2AFZ (K7) Antibody

Purification: Antigen Affinity Purified

Immunogen: Peptide sequence around site of Acetyl-Lys (7) derived from Human Histone H2A.Z

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Alternative Name: H2AFZ

Background:

Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

Aliases: H2A histone family member Z antibody, H2A.z antibody, H2A/z antibody, H2afz antibody, H2AZ antibody, H2AZ_HUMAN antibody, Histone H2A.Z antibody, MGC117173 antibody

UniProt: P0C0S5

Pathways: Telomere Maintenance