PPP1CC antibody

Catalog No. ABIN7140342

The Mouse Monoclonal anti-PPP1CC antibody is suitable to detect PPP1CC in samples from Human. It has been validated for WB and ELISA.

Quick Overview for PPP1CC antibody (ABIN7140342)

Target: PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPP1CC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PPP1CC Antibody

Purpose: PPP1CC Monoclonal Antibody

Purification: Affinity purified

Immunogen: Purified recombinant human PPP1CC protein fragments expressed in E.coli.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: buffer containing 0.1M Tris-Glycine( pH 7.4,150 mM NaCl)with 0.2 % sodium azide,0.1 mg/mLBSA and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PPP1CC

Target: PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))

Alternative Name: PPP1CC

Background:

Background: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.Protein phosphatase 1(PP1)is essential for cell division,and participates in the regulation of glycogen metabolism,muscle contractility and protein synthesis.Dephosphorylates RPS6KB1.Involved in regulation of ionic conductances and long-term synaptic plasticity.May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.Component of the PTW/PP1 phosphatase complex,which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.

Aliases: EC 3.1.3.16, PP 1G, PP-1G, PP1G, PP1G_HUMAN, PP1gamma, PPP 1G, PPP1CC, PPP1CC protein, PPP1G, Protein phosphatase 1 catalytic subunit gamma isoform, Protein phosphatase 1C catalytic subunit, Protein phosphatase 1C subunit

UniProt: P36873

Pathways: Cellular Glucan Metabolic Process, Lipid Metabolism