TGFB1 antibody (AA 279-390)

Catalog No. ABIN7140875

This Rabbit Polyclonal antibody specifically detects TGFB1 in ELISA. It exhibits reactivity toward Cow.

Quick Overview for TGFB1 antibody (AA 279-390) (ABIN7140875)

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Reactivity: Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFB1 antibody is un-conjugated

Application: ELISA

Product Details anti-TGFB1 Antibody

Binding Specificity: AA 279-390

Cross-Reactivity: Cow

Purification: >95%, Protein G purified

Immunogen: Recombinant Bovine Transforming growth factor beta-1 proprotein protein (279-390AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TGFB1

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Alternative Name: TGFB1

Background:

Background: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts (By similarity).

Aliases: TGFB1 antibody, Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide antibody, LAP), Transforming growth factor beta-1 antibody, TGF-beta-1)] antibody

UniProt: P18341

Pathways: EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints