PSMC6 antibody (Regulatory Subunit 10B)

Catalog No. ABIN7142226

Product Details anti-PSMC6 Antibody

Target: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Binding Specificity: AA 1-260, Regulatory Subunit 10B

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMC6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human 26S proteasome regulatory subunit 10B protein (1-260AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PSMC6

Target: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Alternative Name: PSMC6 (PSMC6 Products)

Synonyms: DDBDRAFT_0186051 antibody, DDBDRAFT_0232968 antibody, DDB_0186051 antibody, DDB_0232968 antibody, fb20g04 antibody, wu:fb20g04 antibody, wu:fc85c10 antibody, cadp44 antibody, sug2 antibody, PSMC6 antibody, psmc6-a antibody, NV13405 antibody, CADP44 antibody, P44 antibody, SUG2 antibody, p42 antibody, 2300001E01Rik antibody, AI451058 antibody, 26S protease regulatory subunit S10B antibody, 26S proteasome regulatory subunit 10B antibody, proteasome 26S subunit, ATPase 6 antibody, proteasome 26S subunit, ATPase 6 L homeolog antibody, 26S protease regulatory subunit 10B antibody, proteasome 26S subunit, ATPase 6 S homeolog antibody, proteasome (prosome, macropain) 26S subunit, ATPase, 6 antibody, ATEG_02903 antibody, HCAG_04181 antibody, LOC5565051 antibody, EDI_289460 antibody, CpipJ_CPIJ003334 antibody, EHI_194070 antibody, PTRG_02716 antibody, BDBG_01801 antibody, psmC6 antibody, MCYG_07206 antibody, PITG_00229 antibody, VDBG_04729 antibody, MGYG_04704 antibody, TERG_01608 antibody, DICPUDRAFT_97252 antibody, Tsp_02519 antibody, prs10 antibody, LOC100282100 antibody, Psmc6 antibody, psmc6 antibody, psmc6.L antibody, PSMC6 antibody, LOC693577 antibody, psmc6.S antibody, LOC100117671 antibody

Background:

Background: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.

Aliases: 26S protease regulatory subunit 10B antibody, 26S protease regulatory subunit S10B antibody, 26S proteasome AAA-ATPase subunit RPT4 antibody, CADP44 antibody, P44 antibody, Proteasome 26S subunit ATPase 6 antibody, Proteasome subunit p42 antibody, PRS10_HUMAN antibody, PSMC6 antibody, Rpt4 antibody, SUG2 antibody

UniProt: P62333

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway